Primary Bone Cancer:There are 3 main types of primary bone cancer / sarcoma: Osteosarcoma = Bone forming Chondrosarcoma = Cartilage forming Ewings Sarcoma = Small round blue cells growth in bone and soft tissues For more information, please visit:

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Osteosarcoma:Osteosarcoma is the most common between the ages of 10 to 30 and those > 60 years old. There is no known cause in majority of patients but certain factors are known to increase your risk eg. previous radiotherapy, paget's disease, fibrous dysplasia, bone infarcts or Li Fraumeni syndrome. Most occur around the knee but can occur in any bone. Treatment generally involves combination of chemotherapy and surgery.

Chondrosarcoma:This is the second most common type of primary bone cancer, particularly over the age of 40. It often develops from normal cartilage cells or may occur in patients with pre-existing benign cartilage tumours eg. enchondromas, multiple osteochondromas, Ollier or Maffucci syndrome. Most occur in the femur, humerus, pelvis and around the knee but can occur in any bone. Most patients are treated with surgery alone as these are generally not responsive to chemotherapy or radiotherapy.

Ewings Sarcoma:Ewing's sarcoma is the second most common bone cancer in children and young adults. There is no known cause but has a characteristic change in the cells' chromosome which is not inherited. It is most common in long bones but can occur in any bone. This tumour is generally treated with combined chemotherapy, surgery and occasionally with radiotherapy.

Treatment: Management of these tumours are quite complex and requires specialist management involving a team of experienced clinicians (Orthopaedic oncology surgeon, Radiation oncologist, Medical Oncologist and Plastics Reconstructive surgeon). Surgery is the mainstay of treatment and requires resection of the sarcoma with a cuff surrounding healthy tissue to ensure the tumour has been completely excised. Plastics surgeons assist with reconstruction of the defect and to restore loss function. Radiotherapy may be considered, particularly given most sarcomas are sensitive to radiation therapy. This can be given before or after surgery depending on a number of factors that your surgeon with discuss with you. Chemotherapy is not routinely used in soft tissue sarcomas. It is, however, considered depending on the patient and certain types of sarcoma. For more information, please visit: